Although the N64 is not specifically a General MIDI device, it can be configured as one. As part of the developer's kit, there is a General MIDI Bank that demonstrates this. All the sound files used in this bank are also provided and may be used by licensed developers in any N64 project.
Currently, MIDI channel 10 is configured to default to program 128. In the General Midi Bank, this is the Standard Drum Kit. If you send a program change on channel 10, the specified program will be selected, and channel 10 will no longer be the Standard Drum Kit.